Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587255 | 0.87 | ABL1 (0.38) | PTGER4ABL1HPDALDH1A1TSHR | |
| SCHEMBL19700944 | 0.81 | ALDH1A1 (0.41) | PTGER4ABL1ALDH1A1TSHRPTGS2 | |
| SCHEMBL17689718 | 0.80 | ABL1 (0.44) | PTGER4ABL1ALDH1A1TSHRPTGS2 | |
| SCHEMBL8312122 | 0.79 | HPD (0.36) | HPDKDM4ENPC1L3MBTL1HDAC3 | |
| SCHEMBL24744904 | 0.77 | ATR (0.41) | PTGER4ABL1HPDALDH1A1TSHR | |
| SCHEMBL30121806 | 0.77 | ATR (0.41) | PTGER4ABL1HPDALDH1A1TSHR | |
| SCHEMBL587100 | 0.77 | TP53 (0.44) | PTGER4ALDH1A1TSHRGAAKDM4E | |
| SCHEMBL10610948 | 0.76 | ABL1 (0.49) | PTGER4ABL1ALDH1A1TSHRPTGS2 | |
| SCHEMBL588042 | 0.75 | CYP4F2 (0.46) | ALDH1A1TSHRSMN1; SMN2NPC1MEN1 | |
| SCHEMBL8312126 | 0.75 | HPD (0.34) | HPDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864219-B2 | Substituted aryl ketones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |
| US-20050009704-A1 | Substituted aryl ketones | SCHALLNER OTTO (DE) | 2005-01-13 | — | — | US | disclosed |
| US-20030153465-A1 | Substituted aryl ketones | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009704-A1 | Substituted aryl ketones | CBR3, CBR1, CYCS | PTGER4 1342/4885ABL1 1199/4885HPD 1471/4885 |
| US-20030153465-A1 | Substituted aryl ketones | CBR1, CBR3, CYCS | PTGER4 1626/4885ABL1 1584/4885HPD 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.