Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305850 | 0.70 | GLP1R (0.41) | GLP1R | |
| SCHEMBL6307488 | 0.69 | GLP1R (0.59) | GLP1RGAA | |
| SCHEMBL6304446 | 0.63 | ALDH1A1 (0.46) | GAA | |
| SCHEMBL14486902 | 0.63 | ALDH1A1 (0.41) | — | |
| SCHEMBL16526249 | 0.58 | ALDH1A1 (0.36) | — | |
| SCHEMBL6303925 | 0.58 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6312923 | 0.56 | GLP1R (0.71) | GLP1R | |
| SCHEMBL11116507 | 0.56 | ALDH1A1 (0.39) | — | |
| SCHEMBL10975195 | 0.56 | ALDH1A1 (0.39) | — | |
| SCHEMBL11870814 | 0.55 | CUL4A (0.50) | GAAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |