Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Methylbutanal SCHEMBL6024917 | 0.88 | MAPT (0.48) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL23151968 | 0.87 | ESR1 (0.54) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL18334312 | 0.85 | CYP2D6 (0.49) | ALDH1A1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL7142990 | 0.83 | NPC1 (0.55) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL23486834 | 0.81 | CYP1A2 (0.58) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6024270 | 0.81 | LMNA (0.41) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL6024273 | 0.81 | LMNA (0.41) | MAPTNPC1RAB9AALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL11639381 | 0.81 | CYP1A2 (0.56) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL25645511 | 0.80 | NPC1 (0.43) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL19288474 | 0.80 | LMNA (0.50) | MAPTNPC1ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129204-B2 | Perfumes | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2006-10-31 | — | — | US | claimed |
| EP-1286651-B1 | USE OF AMINOBENZOIC ACIDS IN COMPOSITIONS WITH PERFUMES | QUEST INT SERV BV (NL) | 2006-08-02 | — | — | EP | claimed |
| US-20030199422-A1 | Perfumes | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2003-10-23 | — | — | US | claimed |
| EP-1286651-A1 | IMPROVEMENTS IN OR RELATING TO PERFUMES | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2003-03-05 | — | — | EP | claimed |
| WO-2001093823-A1 | IMPROVEMENTS IN OR RELATING TO PERFUMES | QUEST INTERNATIONAL B.V. (NL) | 2001-12-13 | — | — | WO | claimed |
| US-11033481-B2 | Silicone resin, making method, and cosmetics | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-06-15 | — | — | US | disclosed |
| US-10765619-B2 | Silicone resin, making method, and cosmetics | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-09-08 | — | — | US | disclosed |
| US-20200078289-A1 | SILICONE RESIN, MAKING METHOD, AND COSMETICS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-2505602-B1 | Organopolysiloxane and cosmetic containing it | SHINETSU CHEMICAL CO (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-8697042-B2 | Organopolysiloxane and cosmetic containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-04-15 | — | — | US | disclosed |
| EP-2103301-B1 | Polyglycerin-modified silicone and a cosmetic comprising the same | SHINETSU CHEMICAL CO (JP) | 2013-02-13 | — | — | EP | disclosed |
| US-20120252757-A1 | ORGANOPOLYSILOXANE AND COSMETIC CONTAINING IT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20070196291-A1 | Cosmetic comprising a silicone polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-08-23 | — | — | US | disclosed |
| EP-1736138-A1 | COSMETIC PREPARATION CONTAINING SILICONE POLYMER | Shin-Etsu Chemical Company, Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-7129204-B2 | Perfumes | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2006-10-31 | — | — | US | disclosed |
| EP-1286651-B1 | USE OF AMINOBENZOIC ACIDS IN COMPOSITIONS WITH PERFUMES | QUEST INT SERV BV (NL) | 2006-08-02 | — | — | EP | disclosed |
| EP-1424373-A2 | Hydrophilized powder and a composition comprising the same | Shin-Etsu Chemical Company, Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-20030199422-A1 | Perfumes | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2003-10-23 | — | — | US | disclosed |
| EP-1286651-A1 | IMPROVEMENTS IN OR RELATING TO PERFUMES | QUEST INTERNATIONAL NEDERLAND BV (NL) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093823-A1 | IMPROVEMENTS IN OR RELATING TO PERFUMES | QUEST INTERNATIONAL B.V. (NL) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196291-A1 | Cosmetic comprising a silicone polymer | PRMT7, KAT7, SRRM2 | MAPT 4525/4885NPC1 3963/4885RAB9A 4319/4885 |
| US-20120252757-A1 | ORGANOPOLYSILOXANE AND COSMETIC CONTAINING IT | RAD54L, OR10J3, H1-0 | MAPT 4803/4885NPC1 3307/4885RAB9A 3537/4885 |
| US-20030199422-A1 | Perfumes | PAH, PIR, TRPA1 | MAPT 1098/4885NPC1 3760/4885RAB9A 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.