Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10276699 | 0.89 | KIF11 (0.46) | NPC1RAB9APDE4BKIF11SMN1; SMN2 | |
| SCHEMBL3607590 | 0.87 | TBXA2R (0.51) | KIF11HDAC3HDAC1MAPK1ALDH1A1 | |
| SCHEMBL7168986 | 0.86 | KIF11 (0.52) | KIF11SMN1; SMN2HDAC3HDAC1PPARA | |
| SCHEMBL10309879 | 0.85 | KIF11 (0.45) | NPC1RAB9AKIF11SMN1; SMN2KCNH2 | |
| SCHEMBL8053146 | 0.85 | KIF11 (0.45) | NPC1RAB9AKIF11SMN1; SMN2KCNH2 | |
| SCHEMBL6302955 | 0.85 | KIF11 (0.45) | NPC1RAB9AKIF11SMN1; SMN2KCNH2 | |
| SCHEMBL6476023 | 0.83 | KIF11 (0.43) | NPC1RAB9AKIF11SMN1; SMN2MAPK1 | |
| SCHEMBL8040236 | 0.82 | KIF11 (0.44) | NPC1RAB9AKIF11SMN1; SMN2KCNH2 | |
| SCHEMBL3921295 | 0.82 | KIF11 (0.44) | NPC1RAB9AKIF11SMN1; SMN2KCNH2 | |
| SCHEMBL12049184 | 0.82 | KIF11 (0.58) | NPC1RAB9AKIF11SMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147367-A1 | SMALL MOLECULE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2017-03-29 | — | — | EP | disclosed |
| US-6951930-B2 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-20030113765-A1 | Hybridization-triggered fluorescent detection of nucleic acids | EPOCH BIOSCIENCES, INC. (US) | 2003-06-19 | — | — | US | disclosed |
| US-6472153-B1 | COVALENTLY BOUND OLIGONUCLEOTIDE/MINOR GROOVE BINDER/LATENT FLUOROPHORE COMBINATION | EPOCH BIOSCIENCES, INC. | 2002-10-29 | — | — | US | disclosed |
| EP-1224332-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | Epoch Biosciences, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001031063-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | EPOCH BIOSCIENCES, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113765-A1 | Hybridization-triggered fluorescent detection of nucleic acids | DDX21, RNGTT, NOP2 | NPC1 2391/4885RAB9A 4224/4885PDE4B 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.