Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305649 | 1.00 | CYP2C9 (0.57) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28882651 | 0.93 | CYP2C9 (0.54) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL4906704 | 0.85 | CYP2C9 (0.69) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL4961560 | 0.85 | CYP2C9 (0.69) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL2755215 | 0.85 | CYP2C9 (0.69) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28638384 | 0.83 | CYP2C9 (0.54) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL7110384 | 0.81 | PTP4A1 (0.44) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL7110389 | 0.81 | PTP4A1 (0.44) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL9869805 | 0.81 | CYP2C9 (0.66) | CYP2C9MAPTMEN1KMT2ARAB9A | |
| SCHEMBL15491442 | 0.81 | CYP2C9 (0.66) | CYP2C9MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054748-A1 | Comprising a mono- and/or a polycyanoacrylate, a polymerizable monomer, a stabilizer, an initiator, pigments and a filling material; usable as dental filling material, dental cement, dental sealer or as dental adhesives; also usable in microelectronics as industrial adhesives or for medical applications | KLEE JOACHIM E (DE) | 2005-03-10 | — | — | US | disclosed |
| US-20020147249-A1 | Dental composition | DENTSPLY RESEARCH & DEVELOPMENT CORP. | 2002-10-10 | — | — | US | disclosed |
| US-20020025993-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2002-02-28 | — | — | US | disclosed |
| EP-1137389-A1 | DENTAL COMPOSITION | DENTSPLY INTERNATIONAL, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000033793-A1 | DENTAL COMPOSITION | DENTSPLY INTERNATIONAL INC. (US) | 2000-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147249-A1 | Dental composition | CAD, SMCHD1, FHIT | CYP2C9 1909/4885MAPT 140/4885MEN1 1253/4885 |
| US-20050054748-A1 | Comprising a mono- and/or a polycyanoacrylate, a polymerizable monomer, a stabilizer, an initiator, pigments and a filling material; usable as dental filling material, dental cement, dental sealer or as dental adhesives; also usable in microelectronics as industrial adhesives or for medical applications | KCNMA1, CAD, PUF60 | CYP2C9 3590/4885MAPT 553/4885MEN1 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.