Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.51 |
| ▸ | TEK | Q02763 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628059 | 0.90 | RAF1 (0.59) | KDRCA9CA7RAF1BRAF | |
| SCHEMBL3944252 | 0.86 | KDR (0.64) | KDRTRPV1CA9CA1CA2 | |
| SCHEMBL6308055 | 0.86 | SMN1; SMN2 (0.61) | TRPV1NPC1CASP3RAB9ASENP7 | |
| SCHEMBL6312736 | 0.85 | TRPV1 (0.54) | KDRTRPV1NPC1CASP3RAB9A | |
| SCHEMBL6313267 | 0.82 | RAB9A (0.56) | KDRTRPV1NPC1CASP3RAB9A | |
| SCHEMBL18824175 | 0.81 | KDR (0.58) | KDRTRPV1CA9CA1CA2 | |
| SCHEMBL6305970 | 0.81 | MAPT (0.65) | KDRTRPV1NPC1CASP3RAB9A | |
| SCHEMBL29364392 | 0.80 | KDR (1.00) | KDRTRPV1CA9CA1CA2 | |
| SCHEMBL118026 | 0.80 | KDR (1.00) | KDRTRPV1CA9CA1CA2 | |
| SCHEMBL4920329 | 0.79 | TRPV1 (0.65) | TRPV1NPC1CASP3RAB9ASENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119304-A1 | Urea derivatives | BAYER HEALTHCARE AG (DE) | 2005-06-02 | — | — | US | claimed |
| US-20050119304-A1 | Urea derivatives | BAYER HEALTHCARE AG (DE) | 2005-06-02 | — | — | US | disclosed |
| EP-1465623-A1 | UREA DERIVATIVES | Bayer HealthCare AG (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003055484-A1 | UREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119304-A1 | Urea derivatives | SLC14A1, UBA1, UFM1 | KDR 1831/4885TRPV1 84/4885NPC1 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.