Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308055 | 0.91 | SMN1; SMN2 (0.61) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL6305909 | 0.82 | KDR (0.64) | RAB9ANPC1CASP3SENP7TRPV1 | |
| SCHEMBL6308329 | 0.82 | RAB9A (0.55) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL6306822 | 0.82 | RAB9A (0.64) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL4920329 | 0.82 | TRPV1 (0.65) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL5798843 | 0.81 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL6314690 | 0.81 | IMPDH2 (0.57) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL6305211 | 0.81 | MAPT (0.63) | RAB9ASMN1; SMN2NPC1CASP3SENP7 | |
| SCHEMBL30577265 | 0.80 | SMN1; SMN2 (0.81) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL4011536 | 0.79 | LDHA (0.78) | RAB9ASMN1; SMN2NPC1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119304-A1 | Urea derivatives | BAYER HEALTHCARE AG (DE) | 2005-06-02 | — | — | US | claimed |
| EP-1465623-A1 | UREA DERIVATIVES | Bayer HealthCare AG (DE) | 2004-10-13 | — | — | EP | claimed |
| WO-2003055484-A1 | UREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | claimed |
| US-20050119304-A1 | Urea derivatives | BAYER HEALTHCARE AG (DE) | 2005-06-02 | — | — | US | disclosed |
| EP-1465623-A1 | UREA DERIVATIVES | Bayer HealthCare AG (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003055484-A1 | UREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119304-A1 | Urea derivatives | SLC14A1, UBA1, UFM1 | RAB9A 1907/4885SMN1; SMN2 1077/4885NPC1 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.