Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303827 | 0.85 | NPC1 (0.46) | GLP1RMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6304415 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1POLBKDM4ELMNA | |
| SCHEMBL6303980 | 0.72 | ALDH1A1 (0.49) | MAPTALDH1A1POLBKDM4ELMNA | |
| SCHEMBL6304106 | 0.71 | GLP1R (0.58) | GLP1RMAPTALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL9823116 | 0.68 | TDP1 (0.69) | MAPTALDH1A1POLBKDM4ELMNA | |
| SCHEMBL15196669 | 0.65 | RAB9A (0.61) | MAPTALDH1A1POLBKDM4ELMNA | |
| SCHEMBL8043918 | 0.64 | MAPT (0.45) | MAPTALDH1A1POLBLMNAMEN1 | |
| SCHEMBL6307894 | 0.63 | ALDH1A1 (0.60) | MAPTALDH1A1POLBKDM4ELMNA | |
| SCHEMBL6304274 | 0.63 | ALDH1A1 (0.59) | MAPTALDH1A1POLBKDM4ELMNA | |
| SCHEMBL8764992 | 0.63 | RAB9A (0.58) | MAPTALDH1A1POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |