Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304064 | 0.77 | NQO2 (0.39) | CNR2NQO2MTNR1ACACNA1BAPBA1 | |
| SCHEMBL6306590 | 0.74 | MTNR1A (0.37) | CNR2NQO2MTNR1ACACNA1BAPBA1 | |
| SCHEMBL6303858 | 0.73 | CNR2 (0.38) | CNR2NQO2MTNR1ACACNA1BAPBA1 | |
| SCHEMBL6306592 | 0.73 | MTNR1A (0.36) | CNR2NQO2MTNR1ACACNA1BAPBA1 | |
| SCHEMBL6306600 | 0.72 | NQO2 (0.33) | NQO2MTNR1AADRB2ADRB1ADRB3 | |
| SCHEMBL974720 | 0.69 | NR4A1 (0.53) | ADRB2ADRB1ADRB3CDC25BKDM4E | |
| SCHEMBL1204440 | 0.68 | KDM4E (0.56) | MTNR1AADRB2ADRB1ADRB3CDC25B | |
| SCHEMBL6235824 | 0.67 | CYP4F2 (0.38) | CACNA1BAPBA1ADRB2ADRB1ADRB3 | |
| SCHEMBL31395544 | 0.67 | KDM4E (0.54) | MTNR1AADRB2ADRB1ADRB3CDC25B | |
| SCHEMBL14627192 | 0.66 | AR (0.41) | ADRB2ADRB1ADRB3CDC25BSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943267-B1 | compounds structurally resemble the substrates of the enzymes, but have nonhydrolyzable mono protonated thiophosphonate salts; chromatography or distillations not required | UTAH STATE UNIVERSITY (US) | 2005-09-13 | — | — | US | disclosed |
| US-20050049431-A1 | Thiophosphonate inhibitors of phosphatase enzymes and metallophosphatases | UTAH STATE UNIVERSITY | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049431-A1 | Thiophosphonate inhibitors of phosphatase enzymes and metallophosphatases | PPME1, MTMR1, PTPRE | CNR2 4521/4885NQO2 945/4885MTNR1A 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.