Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Docosanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetostearyl Alcohol SCHEMBL28668273 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL9782972 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Decanol SCHEMBL28463807 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| 1-Hexanol SCHEMBL8015503 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL1360724 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Octanol SCHEMBL208036 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL4612309 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Sulfuric Acid SCHEMBL5510760 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Sulfuric Acid SCHEMBL9563634 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Undecanol SCHEMBL16150770 | 1.00 | LMNA (0.72) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243255-B1 | Method of preparation of antibiotic compositions | HERAEUS KULZER GMBH (DE) | 2005-12-07 | — | — | EP | claimed |
| US-6942877-B2 | Method for producing antibiotic composites | HERAEUS KULZER GMBH & CO. KG (DE) | 2005-09-13 | — | — | US | claimed |
| US-20020192279-A1 | Method for producing antibiotic composites | HERAEUS KULZER GMBH & CO.KG (DE) | 2002-12-19 | — | — | US | claimed |
| US-6942877-B2 | Method for producing antibiotic composites | HERAEUS KULZER GMBH & CO. KG (DE) | 2005-09-13 | — | — | US | disclosed |
| US-20020192279-A1 | Method for producing antibiotic composites | HERAEUS KULZER GMBH & CO.KG (DE) | 2002-12-19 | — | — | US | disclosed |