Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839533 | 0.92 | NLRP3 (0.51) | NLRP3SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL1813965 | 0.81 | L3MBTL1 (0.41) | NLRP3SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL7669841 | 0.79 | NLRP3 (0.48) | NLRP3SMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL3019690 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL13996135 | 0.77 | GAA (0.49) | NLRP3KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL1429298 | 0.76 | AKR1B1 (0.55) | NLRP3SMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL2167246 | 0.75 | NLRP3 (0.51) | NLRP3SMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL5489679 | 0.75 | NLRP3 (0.43) | NLRP3SMN1; SMN2KDM4EMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27532390 | 0.75 | AKR1B1 (0.53) | NLRP3SMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL2167805 | 0.74 | KMT2A (0.44) | NLRP3SMN1; SMN2KDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AG (DE) | 2005-07-28 | — | — | US | disclosed |
| US-6858741-B2 | Alkyl-dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-22 | — | — | US | disclosed |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | LIEB FOLKER (DE) | 2003-10-23 | — | — | US | disclosed |
| US-6380246-B1 | FOR COMBATING PESTS AND WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-30 | — | — | US | disclosed |
| US-6316486-B1 | FOR COMBATING PESTS AND WEED | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164885-A1 | Alkyl dihalogenated phenyl-substituted ketoenols useful as pesticides and herbicides | DDT, CYP8B1, PAOX | NLRP3 2071/4885SMN1; SMN2 4806/4885KDM4E 473/4885 |
| US-20030199572-A1 | Alkyl-dihalogenophenyl-substituted ketoenols | CYP2E1, CYP8B1, CYP24A1 | NLRP3 3794/4885SMN1; SMN2 4464/4885KDM4E 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.