Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYBB | P04839 | 5/20 | 0.58 |
| ▸ | NOX4 | Q9NPH5 | 5/20 | 0.58 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.58 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.58 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | USP2 | O75604 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308323 | 0.76 | ALDH1A1 (0.45) | MAPTUSP2MEN1KMT2AALDH1A1 | |
| SCHEMBL6307171 | 0.76 | GAA (0.50) | HTTALDH1A1GAAMAPK1HTR1A | |
| SCHEMBL6307060 | 0.74 | ALDH1A1 (0.64) | HTTMAPTUSP2MEN1KMT2A | |
| SCHEMBL18029452 | 0.74 | CYBB (0.67) | CYBBNOX4NOX1NOX3NOX5 | |
| SCHEMBL17999762 | 0.73 | CYBB (1.00) | CYBBNOX4NOX1NOX3NOX5 | |
| SCHEMBL30100838 | 0.73 | CYBB (1.00) | CYBBNOX4NOX1NOX3NOX5 | |
| SCHEMBL17999785 | 0.72 | CYBB (1.00) | CYBBNOX4NOX1NOX3NOX5 | |
| SCHEMBL17999847 | 0.71 | CYBB (1.00) | CYBBNOX4NOX1NOX3NOX5 | |
| SCHEMBL6314302 | 0.71 | HSP90AA1 (0.41) | MAPTUSP2MEN1KMT2AALDH1A1 | |
| SCHEMBL15662479 | 0.69 | CYBB (1.00) | CYBBNOX4NOX1NOX3NOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919339-B2 | ABCA-1 elevating compounds | CV THEAPEUTICS, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20020128266-A1 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128266-A1 | ABCA-1 elevating compounds | ABCD3, ABCE1, ABCB4 | CYBB 2190/4885NOX4 2557/4885NOX1 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.