Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309273 | 0.79 | TSHR (0.33) | HTR2ATSHRCA1CA2 | |
| SCHEMBL6305363 | 0.66 | HTR2A (0.38) | HTR2AMEN1KMT2AATMTSHR | |
| SCHEMBL6305709 | 0.65 | PSEN1 (0.46) | HTR2ATSHR | |
| SCHEMBL6313205 | 0.65 | PPIA (0.33) | — | |
| SCHEMBL4410716 | 0.63 | PSEN1 (0.40) | HTR2ATSHRCA1CA2 | |
| SCHEMBL6521749 | 0.60 | HTR2A (0.48) | HTR2AMEN1KMT2ACA1CA2 | |
| SCHEMBL29624636 | 0.59 | HTR2A (0.40) | HTR2A | |
| Trifluoroacetic Acid SCHEMBL29065252 | 0.58 | HTR2A (0.42) | HTR2AMEN1KMT2AATMTSHR | |
| SCHEMBL16485222 | 0.56 | KMT2A (0.51) | HTR2AKMT2ACA1CA2 | |
| SCHEMBL13715483 | 0.56 | HTR2A (0.58) | HTR2AKMT2ATSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958330-B1 | Polycyclic α-amino-ε-caprolactams and related compounds | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-25 | — | — | US | disclosed |