Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307367 | 0.90 | HTR7 (0.34) | PPIAAURKAKDRAURKBNPC1 | |
| SCHEMBL6307251 | 0.66 | ACHE (0.36) | PPIAACHEIDO1PTPN1 | |
| SCHEMBL6307606 | 0.66 | PGR (0.42) | KDRIDO1 | |
| SCHEMBL4413444 | 0.64 | KMT2A (0.36) | PPIAACHEIDO1 | |
| Hydrochloric Acid SCHEMBL6314295 | 0.63 | KMT2A (0.36) | PPIAACHEIDO1 | |
| SCHEMBL9463700 | 0.62 | ACHE (0.42) | ACHE | |
| SCHEMBL27818485 | 0.61 | PPIA (0.47) | PPIA | |
| SCHEMBL12017094 | 0.61 | HTR7 (0.45) | PPIA | |
| SCHEMBL8292980 | 0.59 | PSEN1 (0.40) | IDO1 | |
| SCHEMBL23848434 | 0.58 | ACHE (0.40) | ACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958330-B1 | Polycyclic α-amino-ε-caprolactams and related compounds | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-25 | — | — | US | disclosed |