Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | PRKX | P51817 | 1/20 | 0.50 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.44 |
| ▸ | VDR | P11473 | 3/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308035 | 0.91 | MEN1 (0.49) | S1PR1PRKXACVR1S1PR5PPARG | |
| SCHEMBL6301604 | 0.91 | PPARG (0.47) | MRGPRX4PPARGALOX5APACSS2NR1H4 | |
| SCHEMBL6301337 | 0.88 | PPARG (0.51) | PPARGALOX5APACSS2NR1H4VDR | |
| SCHEMBL6167846 | 0.88 | NR4A2 (0.52) | PPARGNR4A2NR1H4VDRNR4A1 | |
| SCHEMBL6303584 | 0.87 | PPARG (0.56) | PPARGALOX5APNR1H4VDR | |
| SCHEMBL6301097 | 0.87 | PPARG (0.52) | PPARGALOX5APACSS2KMT2ANR1H4 | |
| SCHEMBL6307804 | 0.86 | PPARG (0.54) | S1PR1PRKXACVR1S1PR5PPARG | |
| SCHEMBL6308619 | 0.86 | DCTPP1 (0.51) | MRGPRX4PPARGALOX5AP | |
| SCHEMBL7660169 | 0.86 | PTGER1 (0.44) | MRGPRX4PPARGALOX5APMEN1KMT2A | |
| SCHEMBL6301607 | 0.86 | PPARG (0.58) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |