Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 5/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13726768 | 0.80 | F10 (0.58) | F10 | |
| SCHEMBL3828763 | 0.76 | F10 (0.49) | PARP1F10TYK2 | |
| SCHEMBL13725870 | 0.76 | F10 (0.62) | F10 | |
| SCHEMBL3833337 | 0.74 | F10 (0.71) | F10 | |
| SCHEMBL24012079 | 0.71 | CTSC (0.41) | CTSC | |
| SCHEMBL14039674 | 0.69 | F10 (0.50) | F10 | |
| SCHEMBL14320133 | 0.66 | CTSC (0.42) | CTSCNPC1RAB9A | |
| SCHEMBL3014073 | 0.66 | CTSC (0.42) | CTSCNPC1RAB9A | |
| SCHEMBL24012040 | 0.65 | CTSC (0.37) | F10CTSCNPC1RAB9A | |
| SCHEMBL13780946 | 0.65 | F10 (0.48) | F10CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250815-A1 | Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade | WARNER-LAMBERT COMPANY LLC | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250815-A1 | Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade | F12, TFPI, F11 | PARP1 1320/4885F10 9/4885TYK2 4621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.