Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704916 | 0.97 | HSD17B10 (0.35) | HSD17B10PARP1TP53SLC6A2SLC6A4 | |
| SCHEMBL6428132 | 0.92 | RIPK1 (0.36) | HSD17B10PARP1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL6302996 | 0.91 | PARP1 (0.43) | HSD17B10PARP1TP53POLBSMN1; SMN2 | |
| SCHEMBL7708255 | 0.91 | RIPK1 (0.36) | HSD17B10PARP1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL7711006 | 0.90 | PARP1 (0.36) | HSD17B10PARP1TP53POLBSMN1; SMN2 | |
| SCHEMBL6302929 | 0.89 | PARP1 (0.35) | HSD17B10PARP1HDAC3HDAC1HDAC2 | |
| SCHEMBL7708215 | 0.88 | PARP1 (0.42) | HSD17B10PARP1TP53SLC6A2SLC6A4 | |
| SCHEMBL6309617 | 0.87 | HDAC1 (0.43) | HSD17B10PARP1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL6310115 | 0.87 | PARP1 (0.37) | HSD17B10PARP1TP53POLBSMN1; SMN2 | |
| SCHEMBL7704966 | 0.86 | TP53 (0.37) | HSD17B10PARP1TP53POLBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841550-B1 | Benzoxazine and benzothiazine derivatives and their use in medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | disclosed |