Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | AKT2 | P31751 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824963 | 0.88 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL753718 | 0.82 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL27484857 | 0.80 | ALDH1A1 (0.43) | ATMPTGS1PTGS2KDM4EMAPT | |
| SCHEMBL29392787 | 0.80 | TRPA1 (0.42) | ATMMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17220278 | 0.80 | TRPA1 (0.42) | ATMMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28496 | 0.80 | TRPA1 (0.42) | ATMMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL27560479 | 0.80 | NPC1 (0.48) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL9677535 | 0.79 | ALDH1A1 (0.46) | RAB9AMEN1KMT2AATMKDM4E | |
| Methyl Alcohol SCHEMBL28009509 | 0.78 | RAB9A (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| Ethylene SCHEMBL2135101 | 0.78 | TRPA1 (0.41) | ATMMAPTGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289801-A | Oral care gel | 高露洁-棕榄公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-101437488-B | Oral care compositions with silicone composites | COLGATE-PALMOLIVE CO. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-101163523-B | Tooth whitening compositions containing cross-linked polymer-peroxide | COLGATE PALMOLIVE CO | 2013-06-19 | — | — | CN | disclosed |
| EP-1484355-B1 | High solids process for preparing polymeric nanoparticles | ROHM & HAAS (US) | 2012-12-12 | — | — | EP | disclosed |
| CN-101437488-A | Oral care compositions with silicone composites | COLGATE PALMOLIVE CO (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-101163523-A | Tooth whitening compositions containing cross-linked polymer-peroxide | COLGATE PALMOLIVE CO (US) | 2008-04-16 | — | — | CN | disclosed |
| US-6858299-B2 | High solids process for preparing polymeric nanoparticles | ROHM AND HAAS COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1484355-A1 | High solids process for preparing polymeric nanoparticles | ROHM AND HAAS COMPANY (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20040236050-A1 | High solids process for preparing polymeric nanoparticles | ROHN AND HAAS COMPANY | 2004-11-25 | — | — | US | disclosed |