Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311314 | 1.00 | CHRM1 (0.53) | CHRM1CHRM4CHRM5OPRM1OPRD1 | |
| SCHEMBL6315861 | 0.82 | OPRM1 (0.55) | OPRM1OPRD1 | |
| SCHEMBL6316748 | 0.82 | OPRM1 (0.55) | OPRM1OPRD1 | |
| SCHEMBL6308475 | 0.81 | OPRM1 (0.57) | CHRM1OPRM1OPRD1 | |
| SCHEMBL6316657 | 0.79 | OPRM1 (0.60) | CHRM1CHRM4CHRM5OPRM1OPRD1 | |
| SCHEMBL6317143 | 0.78 | OPRM1 (0.53) | OPRM1OPRD1 | |
| SCHEMBL6309557 | 0.75 | OPRM1 (0.69) | OPRM1OPRD1 | |
| SCHEMBL6309551 | 0.75 | OPRM1 (0.69) | OPRM1OPRD1 | |
| SCHEMBL6311692 | 0.74 | OPRM1 (0.52) | OPRM1OPRD1 | |
| SCHEMBL6310224 | 0.73 | OPRM1 (0.79) | OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004163-A1 | 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004163-A1 | 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives | OPRD1, OPRM1, OPRK1 | CHRM1 142/4885CHRM4 314/4885CHRM5 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.