Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311119 | 1.00 | CYP19A1 (0.42) | CYP19A1MAOAMAOBAPPKCNH2 | |
| SCHEMBL21511943 | 0.79 | APP (0.35) | APPALDH1A1 | |
| SCHEMBL20751703 | 0.79 | CYP19A1 (0.41) | CYP19A1MAOAMAOBAPPKCNH2 | |
| SCHEMBL29107949 | 0.77 | ALDH1A1 (0.48) | CYP19A1MAOAMAOBTRPA1NFE2L2 | |
| SCHEMBL6389002 | 0.77 | MEN1 (0.38) | CYP19A1MAOAMAOBAPPTRPA1 | |
| SCHEMBL6388999 | 0.77 | MEN1 (0.38) | CYP19A1MAOAMAOBAPPTRPA1 | |
| SCHEMBL6303896 | 0.77 | CYP19A1 (0.59) | CYP19A1MAOAMAOBTRPA1NFE2L2 | |
| SCHEMBL6303895 | 0.77 | CYP19A1 (0.59) | CYP19A1MAOAMAOBTRPA1NFE2L2 | |
| SCHEMBL8418998 | 0.76 | APP (0.65) | CYP19A1MAOAMAOBAPPKCNH2 | |
| SCHEMBL13177649 | 0.76 | APP (0.65) | CYP19A1MAOAMAOBAPPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849766-B2 | 1,4-diamino-2-alkenylbenzene derivatives, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| EP-1351921-B1 | NOVEL 1,4-DIAMINO-2-ALKENYL-BENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| EP-1351921-A1 | NOVEL 1,4-DIAMINO-2-ALKENYL-BENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-10-15 | — | — | EP | disclosed |
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-03 | — | — | US | disclosed |
| WO-2002057214-A1 | NOVEL 1,4-DIAMINO-2-ALKENYL-BENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | AOC1, AOX1, GPX1 | CYP19A1 2301/4885MAOA 292/4885MAOB 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.