SCHEMBL6311441

SCHEMBL6311441

Cc1cn([C@H]2CC(F)(F)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
ALB P02768 2/20 0.52
BLM P54132 2/20 0.52
ALDH1A1 P00352 1/20 0.52
POLB P06746 1/20 0.52
ADRA1A P35348 1/20 0.52
TK1 P04183 5/20 0.52
TSHR P16473 2/20 0.50
PKM P14618 1/20 0.50
PMP22 Q01453 1/20 0.50
CYP2D6 P10635 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6311439 1.00 LMNA (0.52) LMNAALBBLMALDH1A1POLB
SCHEMBL6754526 1.00 LMNA (0.52) LMNAALBBLMALDH1A1POLB
SCHEMBL6312398 1.00 LMNA (0.52) LMNAALBBLMALDH1A1POLB
SCHEMBL2056628 0.89 LMNA (0.51) LMNAALBBLMALDH1A1POLB
SCHEMBL14664272 0.86 LMNA (0.53) LMNAALBBLMALDH1A1POLB
SCHEMBL14664299 0.86 LMNA (0.53) LMNAALBBLMALDH1A1POLB
SCHEMBL14664273 0.86 LMNA (0.53) LMNAALBBLMALDH1A1POLB
SCHEMBL6394877 0.85 LMNA (0.52) LMNAALBBLMALDH1A1POLB
SCHEMBL5086587 0.85 LMNA (0.52) LMNAALBBLMALDH1A1POLB
SCHEMBL6889312 0.85 LMNA (0.52) LMNAALBBLMALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240220911-A1 SYSTEMS AND METHODS FOR LAST-MILE DELIVERY ASSIGNMENT WALMART APOLLO, LLC 2024-07-04 US claimed
US-20250086816-A1 INFORMATION PROCESSING APPARATUS, GENERATION METHOD, AND COMPUTER PROGRAM PRODUCT KABUSHIKI KAISHA TOSHIBA (JP) 2025-03-13 US disclosed
CN-222597432-U Oil gas pipeline detects positioner 广东石油化工学院 2025-03-11 CN disclosed
US-20240220911-A1 SYSTEMS AND METHODS FOR LAST-MILE DELIVERY ASSIGNMENT WALMART APOLLO, LLC 2024-07-04 US disclosed
US-6949522-B2 β-2′- or 3′-halonucleosides PHARMASSET, INC. (US) 2005-09-27 US disclosed
US-20050119286-A1 BETA-2'-OR 3'-HALONUCLEOSIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-02 US disclosed
EP-1478322-A2 Beta-2'-OR 3'-HALONUCLEOSIDES Pharmasset Limited (BB) 2004-11-24 EP disclosed
US-6784161-B2 VIRICIDES FOR HEPATITIS C BIOCHEM PHARMA, INC. (CA) 2004-08-31 US disclosed
WO-2003000200-A2 β-2'-OR 3'-HALONUCLEOSIDES PHARMASSET LTD. (BB) 2003-01-03 WO disclosed
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues VIROCHEM PHARMA INC. (CA) 2002-02-14 US disclosed
US-5846516-A Perfluoroalkylated amphiphilic phosphorus compounds: preparation and biomedical applications ALLIANCE PHARMACEUTIAL CORP. (US) 1998-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019363-A1 Method for the treatment or prevention of flavivirus infections using nucleoside analogues NUDT1, HAVCR2, SLC28A1 LMNA 1516/4885ALB 1932/4885BLM 825/4885
US-20050119286-A1 BETA-2'-OR 3'-HALONUCLEOSIDES MKI67, EBP, PCNA LMNA 211/4885ALB 3948/4885BLM 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.