Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4217831 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1ADAM17NPSR1 | |
| SCHEMBL4217833 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1ADAM17NPSR1 | |
| SCHEMBL2516744 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1MAOAMAOB | |
| SCHEMBL6310797 | 0.76 | NPSR1 (0.49) | ALDH1A1KMT2AMEN1NPSR1GAA | |
| SCHEMBL6310795 | 0.76 | NPSR1 (0.49) | ALDH1A1KMT2AMEN1NPSR1GAA | |
| SCHEMBL1036337 | 0.75 | NPSR1 (0.43) | ALDH1A1KMT2AMEN1NPSR1GAA | |
| SCHEMBL1036338 | 0.75 | NPSR1 (0.43) | ALDH1A1KMT2AMEN1NPSR1GAA | |
| SCHEMBL5770264 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1NPSR1GAA | |
| SCHEMBL5770254 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1NPSR1GAA | |
| SCHEMBL5770247 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043354-A1 | NK1 antagonist | PFIZER INC | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043354-A1 | NK1 antagonist | TACR2, TACR1, TAC3 | ALDH1A1 2855/4885KMT2A 944/4885MEN1 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.