Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60696 | 0.82 | GABRA1 (0.38) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL16440037 | 0.79 | TSHR (0.35) | GABRA1TSHRGABRB2 | |
| SCHEMBL29205117 | 0.78 | FAAH (0.32) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL466363 | 0.78 | FAAH (0.32) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL1066355 | 0.78 | — | — | |
| SCHEMBL208330 | 0.73 | — | — | |
| SCHEMBL403171 | 0.72 | — | — | |
| SCHEMBL16553560 | 0.71 | FAAH (0.31) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL2698492 | 0.71 | CYP1A2 (0.31) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL7548863 | 0.71 | GABRA1 (0.41) | FAAHCA1CA2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952329-A | Catalyst sytem for olefin polymerization comprising phenantroline-comprising iron complexes | BASELL POLYOLEFINE GMBH | 2011-01-19 | — | — | CN | disclosed |
| CN-101903418-A | Phenanthroline-containing complexes | BASELL POLYOLEFINE GMBH | 2010-12-01 | — | — | CN | disclosed |
| CN-1217699-C | Preventives or remedies for arrhythmia | SHIONOGI & CO (JP) | 2005-09-07 | — | — | CN | disclosed |
| CN-1217942-C | Pyrrolidine derivatives having phospholipase A inhibitory activity | SHIONOGI & CO (JP) | 2005-09-07 | — | — | CN | disclosed |
| US-6924301-B1 | Composition for treating or preventing arrhythmia | SHIONOGI & CO., LTD. (JP) | 2005-08-02 | — | — | US | disclosed |
| EP-0976748-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| CN-1411379-A | Preventives or remedies for arrhythmia | SHIONOGI & CO (JP) | 2003-04-16 | — | — | CN | disclosed |
| EP-1240906-A1 | PREVENTIVES OR REMEDIES FOR ARRHYTHMIA | SHIONOGI & CO., LTD. (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-6147100-A | ANTIINFLAMMATORY AGENTS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| CN-1251587-A | Pyrrolidine derivatives having phospholipase A inhibitory activity | SHIONOGI & CO (JP) | 2000-04-26 | — | — | CN | disclosed |
| EP-0976748-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |
| CN-1230184-A | Arylamino fused pyridines and pyrimidines | DU PONT MERCK PHARMA (US) | 1999-09-29 | — | — | CN | disclosed |