SCHEMBL466363

SCHEMBL466363

Cc1[c]c(C(C)C)ccc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
GABRA1 P14867 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
HTR2B P41595 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60696 0.84 GABRA1 (0.38) FAAHCA1CA2LMNACYP1A2
SCHEMBL4076318 0.81 FAAH (0.30) FAAHCA1CA2LMNACYP1A2
SCHEMBL1070040 0.78
SCHEMBL6311798 0.78 FAAH (0.31) FAAHCA1CA2LMNACYP1A2
SCHEMBL8074869 0.78 TSHR (0.36) TSHR
SCHEMBL29205117 0.75 FAAH (0.32) FAAHCA1CA2LMNACYP1A2
SCHEMBL19280 0.74
SCHEMBL2698492 0.73 CYP1A2 (0.31) FAAHCA1CA2LMNACYP1A2
SCHEMBL16553560 0.73 FAAH (0.31) FAAHCA1CA2LMNACYP1A2
SCHEMBL7548863 0.73 GABRA1 (0.41) FAAHCA1CA2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11958042-B2 Reactions of olefin derivatives in the presence of metathesis catalysts UMICORE AG & CO. KG (DE) 2024-04-16 US claimed
US-11794179-B2 Synthesis and characterization of metathesis catalysts UMICORE AG & CO. KG 2023-10-24 US claimed
EP-4194092-A1 SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS Umicore AG & Co. KG (DE) 2023-06-14 EP claimed
EP-3496855-B1 METATHESIS CATALYSTS UMICORE AG & CO KG (DE) 2023-01-18 EP claimed
EP-3503999-B1 SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS UMICORE AG & CO KG (DE) 2022-12-07 EP claimed
CN-109862963-B Synthesis and characterization of Ru alkylidene complexes 优美科股份公司及两合公司 2022-05-24 CN claimed
CN-109641198-B Synthesis and characterization of metathesis catalysts 优美科股份公司及两合公司 2022-04-12 CN claimed
US-20220055025-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS UMICORE AG & CO. KG (DE) 2022-02-24 US claimed
US-11173476-B2 Metathesis catalysts UMICORE AG & CO. KG 2021-11-16 US claimed
US-11161104-B2 Reactions of olefin derivatives in the presence of methathesis catalysts UMICORE AG & CO. KG 2021-11-02 US claimed
EP-1979342-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF Jerini AG (DE) 2008-10-15 EP claimed
WO-2008070934-A1 INHIBITION OF INVERTEBRATES USING LIGANDS THAT MODULATE ECDYSONE RECEPTORS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-06-19 WO claimed
WO-2008070891-A1 LIGANDS FOR THE MODULATION OF ECDYSONE RECEPTORS AND CONTROL OF INSECT GROWTH COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-06-19 WO claimed
US-20080004459-A1 Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-03 US claimed
WO-2007131764-A2 NEW HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2007-11-22 WO claimed
WO-2007088041-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2007-08-09 WO claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-1465600-A Process for preparing additively structured polynorbornene 中国科学院化学研究所 2004-01-07 CN claimed
EP-1301512-A2 BICYCLIC HYDANTOIN DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2003-04-16 EP claimed
WO-2002008227-A2 BICYCLIC HYDANTOIN DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2002-01-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161104-B2 Reactions of olefin derivatives in the presence of methathesis catalysts MDK, MTR, MUSK FAAH 1308/4885CA1 3731/4885CA2 4594/4885
US-11173476-B2 Metathesis catalysts SQLE, FDFT1, COASY FAAH 263/4885CA1 3161/4885CA2 3866/4885
US-20220055025-A1 REACTIONS OF OLEFIN DERIVATIVES IN THE PRESENCE OF METHATHESIS CATALYSTS MDK, MTR, MUSK FAAH 1308/4885CA1 3731/4885CA2 4594/4885
US-11794179-B2 Synthesis and characterization of metathesis catalysts SQLE, FDFT1, FASN FAAH 238/4885CA1 2955/4885CA2 3644/4885
US-11958042-B2 Reactions of olefin derivatives in the presence of metathesis catalysts SYMPK, MDK, HCK FAAH 2056/4885CA1 3425/4885CA2 4518/4885
US-20080004459-A1 Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization PICALM, AP1M1, AP2M1 FAAH 3484/4885CA1 1076/4885CA2 666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.