Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 12/20 | 0.91 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31673865 | 0.77 | GLP1R (1.00) | GLP1R | |
| SCHEMBL2555049 | 0.77 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6311921 | 0.77 | GLP1R (0.60) | GLP1RKIF20BPOLBLMNAHTT | |
| SCHEMBL6305960 | 0.65 | GLP1R (0.74) | GLP1R | |
| SCHEMBL6311574 | 0.65 | GLP1R (0.69) | GLP1RCCNE2CCNE1CDK2 | |
| SCHEMBL20636784 | 0.65 | KIF20B (0.48) | GLP1RKIF20BPOLBHTT | |
| SCHEMBL5819225 | 0.64 | ALDH1A1 (0.61) | GLP1RPOLBLMNAHTTL3MBTL1 | |
| SCHEMBL9768068 | 0.62 | GLP1R (0.45) | GLP1R | |
| SCHEMBL11273612 | 0.62 | GLP1R (0.41) | GLP1RHTT | |
| SCHEMBL3660278 | 0.61 | KIF20B (0.50) | GLP1RKIF20BPOLBHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | claimed |
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |