SCHEMBL6312110

SCHEMBL6312110

O=C1CN(C(Cl)Cl)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.42
TOP2A P11388 3/20 0.39
TOP2B Q02880 3/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PTGS1 P23219 2/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7823878 0.81 CRBN (0.39) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL630915 0.78 TOP2A (0.48) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL16685437 0.76 CRBN (0.40) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL16597500 0.75 TOP2A (0.50) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL378251 0.75 TOP2A (0.50) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL7732788 0.75 CRBN (0.42) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL18148982 0.74 CRBN (0.34) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL631865 0.74 TOP2A (0.45) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL10768553 0.74 TOP2A (0.41) CRBNTOP2ATOP2BALDH1A1MAPT
SCHEMBL6662368 0.72 TOP2A (0.43) CRBNTOP2ATOP2BALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60231739-A None JP disclosed
EP-2079308-B1 METHOD FOR PREVENTING GROWTH OF MICROORGANISMS, AND A COMBINATION FOR THE PREVENTION OF MICROBIAL GROWTH KEMIRA OYJ (FI) 2016-08-17 EP disclosed
CN-100337547-C Disinfecting and deodorizing agent KAO CORP (JP) 2007-09-19 CN disclosed
US-6936220-B2 Disinfecting and deodorizing agent KAO CORPORATION (JP) 2005-08-30 US disclosed
US-6576604-B1 Adhesive cleaning sheet KAO CORPORATION (JP) 2003-06-10 US disclosed
CN-1400865-A Disinfecting and deodorizing agent KAO CORP (JP) 2003-03-05 CN disclosed
EP-1281320-A1 DISINFECTING AND DEODORIZING AGENT Kao Corporation (JP) 2003-02-05 EP disclosed
US-20020179884-A1 Disinfecting and deodorizing agent KAO CORPORATION (JP) 2002-12-05 US disclosed
EP-0488310-A1 Multiple-layered silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1992-06-03 EP disclosed
US-5100704-A Method for making a composite of vulcanized rubber and a urethane elastomer THE YOKOHAMA RUBBER CO., LTD. (JP) 1992-03-31 US disclosed
EP-0404374-A2 Composition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-12-27 EP disclosed
JP-S60231739-A SURFACE TREATMENT OF RUBBER ARTICLE TOYODA GOSEI CO LTD 1985-11-18 JP disclosed
US-4534812-A DI-AND TRI-CHLOROISOCYANURIC ACID AS ANTISTICKING AGENT FOR UNVULCANIZED RUBBER ZEON KOSAN CO., LTD. (JP) 1985-08-13 US disclosed