Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 17/20 | 0.58 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6307693 | 0.87 | GLP1R (0.57) | GLP1R | |
| SCHEMBL6304317 | 0.76 | GLP1R (0.61) | GLP1R | |
| SCHEMBL6304253 | 0.74 | GLP1R (1.00) | GLP1RPGK1 | |
| SCHEMBL6306869 | 0.71 | GLP1R (0.72) | GLP1R | |
| SCHEMBL12720945 | 0.68 | SPR (0.52) | SPR | |
| SCHEMBL6311493 | 0.67 | GLP1R (0.68) | GLP1R | |
| SCHEMBL6305960 | 0.67 | GLP1R (0.74) | GLP1R | |
| SCHEMBL12720875 | 0.67 | SMN1; SMN2 (0.54) | SPR | |
| SCHEMBL31673865 | 0.66 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6311574 | 0.65 | GLP1R (0.69) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | claimed |