SCHEMBL631264

SCHEMBL631264

O=C(O)Cc1cc2ccccc2s1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.61
ASIC3 Q9UHC3 1/20 0.56
LOXL2 Q9Y4K0 1/20 0.56
BCL2L1 Q07817 1/20 0.55
AKR1B1 P15121 1/20 0.54
AGXT P21549 1/20 0.51
ADRB2 P07550 1/20 0.51
GLS O94925 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
RPS6KB2 Q9UBS0 1/20 0.49
HDAC3 O15379 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534459 1.00 CYP2A6 (0.61) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
Benzofuran SCHEMBL28230280 0.87 CYP2A6 (0.47) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL6674653 0.86 CYP2A6 (0.58) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL28666644 0.84 CYP2A6 (0.56) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL29861035 0.84 CYP2A6 (0.56) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL1029348 0.84 CYP2A6 (0.59) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL11215245 0.84 CYP2A6 (0.59) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL31356469 0.84 CYP2A6 (0.59) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL1260041 0.84 CYP2A6 (0.59) CYP2A6ASIC3LOXL2BCL2L1AKR1B1
SCHEMBL4510014 0.82 CYP2A6 (0.58) CYP2A6ASIC3LOXL2BCL2L1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102993068-B Electronic transmission layer polymer for solar cell LIYANG PRODUCTIVITY PROMOTION CT 2015-01-07 CN claimed
CN-102976986-B Method for manufacturing polymer used as electron transfer layer of solar cell LIYANG CITY PRODUCTIVITY PROMOTION CT 2014-12-10 CN claimed
CN-103030581-A Method for manufacturing electron transfer layer in solar cell LIYANG PRODUCTIVITY PROMOTION CT 2013-04-10 CN claimed
CN-102993068-A Electronic transmission layer polymer for solar cell LIYANG PRODUCTIVITY PROMOTION CT 2013-03-27 CN claimed
CN-102976986-A Method for manufacturing polymer used as electron transfer layer of solar cell LIYANG CITY PRODUCTIVITY PROMOTION CT 2013-03-20 CN claimed
CN-102952062-A Substituted benzoheterocyclic compounds and preparation method and application thereof INST MEDICINAL BIOTECHNOLOGY 2013-03-06 CN claimed
CN-102391164-A Diaryl thioether compound, preparation method and anti-tumor application thereof UNIV CENTRAL SOUTH 2012-03-28 CN claimed
US-20090069576-A1 PROCESS FOR PRODUCTION OF 1-(3-(2-(1-BENZOTHIOPHEN-5-YL)-ETHOXY)PROPYL)AZETIDIN-3-OL OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD (JP) 2009-03-12 US claimed
EP-1864978-A1 PROCESS FOR PRODUCTION OF 1-(3-(2-(1-BENZOTHIOPHEN-5-YL)- ETHOXY)PROPYL)AZETIDIN-3-OL OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-12-12 EP claimed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 US disclosed
CN-111018790-B Pyridazinone herbicides FMC公司 2023-09-19 CN disclosed
US-20230257388-A1 GRANZYME B DIRECTED IMAGING AND THERAPY CYTOSITE BIOPHARMA INC. (US) 2023-08-17 US disclosed
US-11667645-B2 Granzyme B directed imaging and therapy CYTOSITE BIOPHARMA INC. (US) 2023-06-06 US disclosed
EP-0122156-A2 Improvements in or relating to benzothienylglycyl cephalosporin derivatives ELI LILLY AND COMPANY (US) 1984-10-17 EP disclosed
EP-0098713-A2 Benzoylpiperazine esters and a process for their production KOWA COMPANY, LTD. (JP) 1984-01-18 EP disclosed
EP-0068563-A2 Heterocyclic acetic acid compounds and compositions for treating bone diseases THE PROCTER & GAMBLE COMPANY (US) 1983-01-05 EP disclosed
US-4346076-A Bis-tetrazoylmethyl substituted cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1982-08-24 US disclosed
EP-0048169-A2 Bis-tetrazoylmethyl substituted cephalosporin antibiotics, their preparation and pharmaceutical formulations containing them ELI LILLY AND COMPANY (US) 1982-03-24 EP disclosed
US-4224330-A Esters and thiolesters of benzothienyl acids ZOECON CORPORATION (US) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090069576-A1 PROCESS FOR PRODUCTION OF 1-(3-(2-(1-BENZOTHIOPHEN-5-YL)-ETHOXY)PROPYL)AZETIDIN-3-OL OR SALTS THEREOF PMP22, ACOX1, PAOX CYP2A6 1393/4885ASIC3 730/4885LOXL2 1637/4885
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CYP2A6 3692/4885ASIC3 4815/4885LOXL2 2217/4885
US-20230257388-A1 GRANZYME B DIRECTED IMAGING AND THERAPY GZMB, PRF1, CTSB CYP2A6 4768/4885ASIC3 4132/4885LOXL2 2036/4885
US-11667645-B2 Granzyme B directed imaging and therapy GZMB, PRF1, CTSB CYP2A6 4768/4885ASIC3 4132/4885LOXL2 2036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.