Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | CCR3 | P51677 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.48 |
| ▸ | ARG1 | P05089 | 2/20 | 0.46 |
| ▸ | ARG2 | P78540 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034063 | 0.81 | MEN1 (0.66) | MEN1KMT2ASIGMAR1MCHR1SMN1; SMN2 | |
| SCHEMBL4039589 | 0.79 | MCHR1 (0.56) | MEN1KMT2ASIGMAR1MCHR1SMN1; SMN2 | |
| SCHEMBL7491507 | 0.78 | MEN1 (0.58) | MEN1KMT2ASIGMAR1MCHR1SMN1; SMN2 | |
| SCHEMBL6312739 | 0.76 | SIGMAR1 (0.76) | MEN1KMT2ASIGMAR1MCHR1SMN1; SMN2 | |
| SCHEMBL13888608 | 0.76 | MEN1 (0.58) | MEN1KMT2ASIGMAR1MCHR1SMN1; SMN2 | |
| SCHEMBL12511819 | 0.75 | SIGMAR1 (0.70) | MEN1KMT2ASIGMAR1MCHR1SMN1; SMN2 | |
| SCHEMBL5056848 | 0.75 | TSHR (0.47) | MEN1KMT2ASIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4036032 | 0.74 | ACHE (0.62) | MEN1KMT2ASIGMAR1SMN1; SMN2HRH1 | |
| SCHEMBL2213082 | 0.74 | SIGMAR1 (0.76) | MEN1KMT2ASIGMAR1MCHR1SMN1; SMN2 | |
| SCHEMBL2238599 | 0.73 | OPRM1 (0.51) | MEN1KMT2ASIGMAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903085-B1 | Substituted piperidine compounds useful as modulators of chemokine receptor activity | ASTRAZENECA, AB (CH) | 2005-06-07 | — | — | US | disclosed |