Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 6/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009626 | 0.86 | CYP1A2 (0.44) | CALM1ALDH1A1CYP3A4 | |
| SCHEMBL427550 | 0.82 | CYP19A1 (0.55) | CALM1CYP19A1AKR1B1PTGS2ALDH1A1 | |
| SCHEMBL918847 | 0.80 | PTGS2 (0.59) | PTGS2ALDH1A1CYP3A4HTR2AHTR2C | |
| SCHEMBL6448298 | 0.80 | HMGCR (0.41) | CALM1CYP19A1PTPN1TUBB4ATUBB | |
| SCHEMBL9491787 | 0.79 | CYP19A1 (0.68) | CALM1CYP19A1PTPN1NOS2TUBB4A | |
| SCHEMBL930954 | 0.79 | CYP1A1 (0.61) | CYP19A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL919069 | 0.79 | CYP1A1 (0.61) | CYP19A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6449528 | 0.79 | ALDH1A1 (0.40) | CALM1CYP19A1PTPN1TUBB4ATUBB | |
| SCHEMBL27947309 | 0.79 | NPC1 (0.48) | CALM1CYP19A1TUBB4ATUBBTUBA3C | |
| SCHEMBL919348 | 0.79 | PTGS2 (0.42) | CYP19A1PTGS2ALDH1A1CYP3A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059733-A1 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | WELICHEM BIOTECH, INC. | 2005-03-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059733-A1 | Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues | NFKBIA, IKBKB, IKBKE | CALM1 2044/4885CYP19A1 2924/4885PTPN1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.