Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313462 | 0.78 | CYP2C19 (0.45) | KDM4EPOLBTDP1ALDH1A1CYP1A1 | |
| SCHEMBL1608851 | 0.78 | POLB (0.72) | KDM4EMEN1KMT2APOLBMAPK1 | |
| SCHEMBL13901436 | 0.77 | KMT2A (0.74) | KDM4EMEN1KMT2APOLBMAPK1 | |
| SCHEMBL2894903 | 0.75 | ALDH1A1 (0.46) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7813549 | 0.74 | GAA (0.60) | MEN1KMT2APOLBTDP1MAPK1 | |
| SCHEMBL3337034 | 0.73 | CYP1A1 (0.65) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7820667 | 0.71 | CA12 (0.53) | KDM4EMEN1KMT2APOLBTDP1 | |
| SCHEMBL3333827 | 0.71 | L3MBTL1 (0.60) | MEN1KMT2APOLBALDH1A1CYP1A1 | |
| SCHEMBL7824542 | 0.71 | MEN1 (0.72) | KDM4EMEN1KMT2APOLBTDP1 | |
| SCHEMBL2897809 | 0.71 | MEN1 (0.48) | KDM4EMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | KDM4E 2371/4885MEN1 733/4885KMT2A 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.