Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900637 | 0.83 | L3MBTL1 (0.47) | MEN1KMT2ARAB9AHTTMAPT | |
| SCHEMBL2894903 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2ARAB9AHTTMAPT | |
| SCHEMBL28316733 | 0.80 | PDK1 (0.46) | RAB9AHTTMAPTLMNAL3MBTL1 | |
| SCHEMBL3828333 | 0.80 | ATR (0.40) | MEN1KMT2ALMNAPDK1PDK2 | |
| SCHEMBL2900503 | 0.79 | KDM4E (0.48) | MEN1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL1447993 | 0.78 | L3MBTL1 (0.46) | RAB9AHTTMAPTLMNAL3MBTL1 | |
| SCHEMBL2903333 | 0.77 | MEN1 (0.48) | MEN1KMT2AHTTLMNAL3MBTL1 | |
| SCHEMBL7470294 | 0.76 | MEN1 (0.74) | MEN1KMT2ARAB9AHTTMAPT | |
| SCHEMBL3535796 | 0.75 | PDK1 (0.68) | MEN1KMT2ARAB9ALMNAL3MBTL1 | |
| SCHEMBL29524443 | 0.75 | PDK1 (0.68) | MEN1KMT2ARAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | MEN1 2671/4885KMT2A 412/4885RAB9A 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.