Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308119 | 0.96 | F11 (0.52) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7551638 | 0.95 | F11 (0.47) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6305993 | 0.92 | TSHR (0.50) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6309491 | 0.91 | F11 (0.60) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6308091 | 0.91 | ALDH1A1 (0.54) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6308063 | 0.89 | ALDH1A1 (0.56) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7554897 | 0.87 | F11 (0.40) | F11ALDH1A1TSHR | |
| SCHEMBL6307391 | 0.87 | F11 (0.55) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6308984 | 0.87 | ALDH1A1 (0.51) | F11ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6309689 | 0.86 | F11 (0.48) | F11ALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890930-B1 | Quinazolinones | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |