Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138036 | 0.84 | — | — | |
| SCHEMBL28636538 | 0.78 | — | — | |
| SCHEMBL5133174 | 0.77 | — | — | |
| SCHEMBL17533843 | 0.77 | FDPS (0.45) | — | |
| SCHEMBL135199 | 0.77 | FDPS (0.45) | — | |
| SCHEMBL2459231 | 0.76 | LPAR2 (0.31) | — | |
| SCHEMBL11599180 | 0.75 | OTC (0.41) | OTC | |
| SCHEMBL10896986 | 0.75 | FDPS (0.32) | — | |
| SCHEMBL28246888 | 0.75 | FDPS (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL28600425 | 0.73 | FDPS (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296583-A | Polyphosphonate-epoxide-urethane | UNIVERSITY OF MICHIGAN (US) | 1994-03-22 | — | — | US | claimed |
| EP-0786970-B1 | CALCIFICATION-RESISTANT BIOPROSTHETIC TISSUE AND METHODS OF MAKING SAME | UNIV MICHIGAN (US) | 2005-12-07 | — | — | EP | disclosed |
| EP-0786970-A4 | CALCIFICATION-RESISTANT BIOPROSTHETIC TISSUE AND METHODS OF MAKING SAME | UNIV MICHIGAN (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0649441-A4 | CALCIFICATION-RESISTANT SYNTHETIC BIOMATERIALS. | UNIV MICHIGAN (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0740683-A4 | CALCIFICATION-RESISTANT BIOMATERIALS | UNIV MICHIGAN (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5674298-A | POLYPHOSPHONATE:POLYEPOXIDE ADDUCT | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0786970-A1 | CALCIFICATION-RESISTANT BIOPROSTHETIC TISSUE AND METHODS OF MAKING SAME | THE UNIVERSITY OF MICHIGAN (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0740683-A1 | CALCIFICATION-RESISTANT BIOMATERIALS | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-11-06 | — | — | EP | disclosed |
| WO-1996013227-A1 | CALCIFICATION-RESISTANT BIOPROSTHETIC TISSUE AND METHODS OF MAKING SAME | UNIVERSITY OF MICHIGAN (US) | 1996-05-09 | — | — | WO | disclosed |
| WO-1995020008-A1 | CALCIFICATION-RESISTANT BIOMATERIALS | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1995-07-27 | — | — | WO | disclosed |
| US-5436291-A | Biocompatible implant of polymer modified with polyphosphonate through epoxide linkage; cardiac valve prostheses; irreversible binding of anticalcification agent to biomaterial | UNIVERSITY OF MICHIGAN, THE BOARD OF . . . (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0649441-A1 | CALCIFICATION-RESISTANT SYNTHETIC BIOMATERIALS | THE UNIVERSITY OF MICHIGAN (US) | 1995-04-26 | — | — | EP | disclosed |
| US-5296583-A | Polyphosphonate-epoxide-urethane | UNIVERSITY OF MICHIGAN (US) | 1994-03-22 | — | — | US | disclosed |
| WO-1994001481-A1 | CALCIFICATION-RESISTANT SYNTHETIC BIOMATERIALS | UNIVERSITY OF MICHIGAN (US) | 1994-01-20 | — | — | WO | disclosed |