Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031009 | 0.86 | NPC1 (0.50) | NPC1RAB9AJAK2PAX8TACR1 | |
| SCHEMBL10782208 | 0.86 | NPC1 (0.50) | NPC1RAB9AJAK2PAX8TACR1 | |
| SCHEMBL3342836 | 0.81 | ALDH1A1 (0.45) | NPC1RAB9ALMNASMN1; SMN2JAK2 | |
| SCHEMBL3342832 | 0.81 | ALDH1A1 (0.45) | NPC1RAB9ALMNASMN1; SMN2JAK2 | |
| SCHEMBL6320603 | 0.77 | SMPD2 (0.44) | CCKBRMMP1MMP3 | |
| SCHEMBL25440275 | 0.77 | NPC1 (0.40) | PPARGPPARANPC1RAB9ALMNA | |
| SCHEMBL7004558 | 0.77 | BCHE (0.47) | CCKBRNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL30893951 | 0.76 | ALDH1A1 (0.43) | PPARGPPARASMN1; SMN2EPHX1 | |
| SCHEMBL6320167 | 0.76 | NAAA (0.39) | NPC1RAB9ALMNASMN1; SMN2JAK2 | |
| SCHEMBL8905955 | 0.76 | PPARG (0.45) | PPARGPPARANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869788-B2 | DNA encoding novel D-aminoacylase and process for producing D-amino acid by using the same | MITSUI CHEMICALS, INC. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1365023-A1 | DNA ENCODING NOVEL D-AMINOACYLASE AND PROCESS FOR PRODUCING D-AMINO ACID BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-20030207436-A1 | Dna encoding novel d-aminoacylase and process for producing d-amino acid by using the same | MITSUI CHEMICALS, INC. (JP) | 2003-11-06 | — | — | US | disclosed |