Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
| ▸ | ATIC | P31939 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.38 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307801 | 0.82 | KDM4E (0.56) | FBP1ATICTDP1KDM4ETP53 | |
| SCHEMBL4954130 | 0.81 | ATIC (0.48) | FBP1ATICTDP1KDM4ETP53 | |
| SCHEMBL756245 | 0.78 | P2RY2 (0.64) | FBP1P2RY2DNPH1PRKAB2TRPM2 | |
| SCHEMBL800310 | 0.78 | KDM4E (0.47) | FBP1ATICTDP1KDM4ETP53 | |
| SCHEMBL11977315 | 0.77 | ATIC (0.82) | FBP1ATICTDP1KDM4ETP53 | |
| SCHEMBL11130784 | 0.77 | SMN1; SMN2 (0.51) | FBP1P2RY2DNPH1PRKAB2TRPM2 | |
| Water SCHEMBL443839 | 0.77 | P2RY2 (0.63) | FBP1P2RY2DNPH1PRKAB2TRPM2 | |
| SCHEMBL11527541 | 0.77 | NT5E (0.59) | FBP1P2RY2DNPH1PRKAB2TRPM2 | |
| SCHEMBL5989372 | 0.77 | NT5E (0.45) | FBP1P2RY2DNPH1PRKAB2TRPM2 | |
| SCHEMBL11134118 | 0.76 | CA5A (0.43) | FBP1P2RY2DNPH1PRKAB2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420049-B2 | Labeled adenosine for use in positron emission tomography | Abraham, Edward H. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20050244331-A1 | Labeled adenosine for use in positron emission tomography | ABRAHAM EDWARD H | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050244331-A1 | Labeled adenosine for use in positron emission tomography | ADA, ADORA2A, SLC35B2 | FBP1 750/4885ATIC 128/4885TDP1 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.