SCHEMBL6315286

SCHEMBL6315286

CC(C)C[C@@H]([C]=O)NC(=O)CN

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSC P53634 3/20 0.43
CACNA2D1 P54289 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CACNB3 P54284 1/20 0.33
CACNA1C Q13936 1/20 0.33
PGR P06401 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CACNA2D2 Q9NY47 1/20 0.33
SLC7A5 Q01650 1/20 0.33
ACACB O00763 1/20 0.33
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
MME P08473 1/20 0.31
PSMB5 P28074 2/20 0.30
LAP3 P28838 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20560494 1.00 CTSC (0.43) CTSCCACNA2D1ALDH1A1CACNB3CACNA1C
SCHEMBL11761746 0.88 PSMB5 (0.42) CTSCPSMB5
SCHEMBL27589724 0.87 MMP9 (0.39) CTSCALDH1A1MMP2MMP9MMP8
SCHEMBL9813486 0.84 CTSL (0.36) CTSCMMP2MMP9MMP8PSMB5
SCHEMBL11136853 0.82 PSMB5 (0.41) CACNA2D1ALDH1A1CACNB3CACNA1CACACB
SCHEMBL7377102 0.82 PSMB5 (0.41) ALDH1A1MMP2MMP9MMP8MME
SCHEMBL4638730 0.78 DPP4 (0.46) CTSCALDH1A1SLC7A5LAP3
SCHEMBL27601749 0.78 DPP4 (0.46) CTSCALDH1A1SLC7A5LAP3
SCHEMBL6558952 0.78 DPP4 (0.46) CTSCALDH1A1SLC7A5LAP3
SCHEMBL1006669 0.78 ALDH1A1 (0.50) ALDH1A1SLC7A5MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1658819-A Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form OREAL (FR) 2005-08-24 CN claimed
EP-1515684-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2005-03-23 EP claimed
WO-2003105788-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2003-12-24 WO claimed
EP-2560486-B1 COMPOSITIONS COMPRISING ENZYME-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF SIGNATURE THERAPEUTICS INC (US) 2018-11-21 EP disclosed
CN-1309720-C Piperazine compounds KOWA CO (JP) 2007-04-11 CN disclosed
CN-1658819-A Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form OREAL (FR) 2005-08-24 CN disclosed
EP-1515684-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2005-03-23 EP disclosed
CN-1520408-A Piperazine compounds ������������ʽ���� 2004-08-11 CN disclosed
WO-2003105788-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2003-12-24 WO disclosed