Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6315636 | 0.82 | DAGLA (0.56) | DAGLAHTTXDHSMN1; SMN2MAPT | |
| SCHEMBL433633 | 0.81 | HTT (0.66) | HTTSMN1; SMN2POLBUSP2LMNA | |
| SCHEMBL7091199 | 0.80 | LMNA (0.64) | HTTSMN1; SMN2POLBUSP2LMNA | |
| SCHEMBL27573148 | 0.78 | DAGLA (0.76) | DAGLASMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL10464100 | 0.76 | DAGLA (0.64) | DAGLAXDHSMN1; SMN2MAPTSMYD3 | |
| SCHEMBL7051953 | 0.75 | DAGLA (0.60) | DAGLAHTTXDHSMN1; SMN2MAPT | |
| SCHEMBL1735989 | 0.75 | MAPT (0.55) | DAGLAHTTXDHSMN1; SMN2MAPT | |
| SCHEMBL11073930 | 0.74 | SMYD3 (0.55) | DAGLAHTTMAPTSMYD3POLB | |
| SCHEMBL9518561 | 0.74 | DAGLA (0.64) | DAGLAXDHSMN1; SMN2MAPTLMNA | |
| SCHEMBL6314740 | 0.74 | NPC1 (0.35) | SMN1; SMN2MEN1KMT2AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014027-A1 | Crosslinked polymer doped with iron oxide; diagnosis of nucleic acids | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | US | claimed |
| US-20050014027-A1 | Crosslinked polymer doped with iron oxide; diagnosis of nucleic acids | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | US | disclosed |
| EP-1155026-A2 | METHOD FOR ISOLATING NUCLEIC ACIDS | Bayer Aktiengesellschaft (DE) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000049031-A2 | METHOD FOR ISOLATING NUCLEIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-24 | — | — | WO | disclosed |