SCHEMBL433633

SCHEMBL433633

C=C(C)C(=O)NCCCc1nc2ccccc2[nH]1

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.66
POLB P06746 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.60
LMNA P02545 2/20 0.57
KDM4E B2RXH2 2/20 0.57
USP2 O75604 1/20 0.54
CHRM1 P11229 1/20 0.53
GAA P10253 1/20 0.53
MAPK1 P28482 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7091199 0.95 LMNA (0.64) HTTPOLBSMN1; SMN2LMNAKDM4E
SCHEMBL13405878 0.88 HTT (0.84) HTTPOLBSMN1; SMN2LMNAKDM4E
SCHEMBL12472614 0.84 HTT (0.67) HTTPOLBSMN1; SMN2LMNAKDM4E
SCHEMBL432107 0.82 POLB (0.62) HTTPOLBSMN1; SMN2LMNAKDM4E
SCHEMBL6316263 0.81 DAGLA (0.58) HTTPOLBSMN1; SMN2LMNAUSP2
SCHEMBL16136353 0.80 HTT (1.00) HTTSMN1; SMN2LMNAGAA
SCHEMBL8329416 0.79 BCHE (0.66) HTTPOLBSMN1; SMN2LMNAKDM4E
SCHEMBL13609799 0.79 ALDH1A1 (0.59) HTTPOLBSMN1; SMN2LMNAKDM4E
SCHEMBL1884521 0.78 POLB (0.72) HTTPOLBSMN1; SMN2KDM4EGAA
SCHEMBL17309682 0.78 GAA (0.63) HTTPOLBSMN1; SMN2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582684-B2 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-01 US claimed
US-12630582-B2 Method for biomaterial purification and kits thereof Life Technologies Corporation (US) 2026-05-19 US disclosed
US-20250367610-A1 Block Copolymers Grafted to Porous Polymeric Substrate SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-12-04 US disclosed
EP-4543575-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE Solventum Intellectual Properties Company (US) 2025-04-30 EP disclosed
EP-2588219-B1 FILTER PLATE ARTICLE HAVING A WATER-ABSORBENT FILTER ASSEMBLY NEOGEN FOOD SAFETY US HOLDCO CORP (US) 2024-05-29 EP disclosed
US-20240059731-A1 Method for Biomaterial Purification and Kits Thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-02-22 US disclosed
US-20240010674-A1 A FILTRATION UNIT AND A METHOD FOR BIOMATERIAL PURIFICATION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-01-11 US disclosed
WO-2023248020-A1 BLOCK COPOLYMERS GRAFTED TO POROUS POLYMERIC SUBSTRATE 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-28 WO disclosed
US-11827864-B2 Wipe with a guanidinyl-containing polymer 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-28 US disclosed
EP-4255917-A1 A FILTRATION UNIT AND A METHOD FOR BIOMATERIAL PURIFICATION 3M Innovative Properties Company (US) 2023-10-11 EP disclosed
US-20070154703-A1 FUNCTIONALIZED SUBSTRATES 3M INNOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
WO-2007075442-A2 METHOD OF MAKING MACROPOROUS ANION EXCHANGE RESINS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO disclosed
US-20070142590-A1 Method of making macroporous anion exchange resins 3M INNOVATIVE PROPERTIES COMPANY 2007-06-21 US disclosed
EP-1750839-A1 MACROPOROUS ION EXCHANGE RESINS 3M Innovative Properties Company (US) 2007-02-14 EP disclosed
US-7098253-B2 particles of hydrophilic, crosslinked copolymers of N,N'-alkylenebis(meth)acrylamide and a sulfonated N,N'-alkylene bisacrylic amide; chromatographic columns, composite materials, filters; large furface area, ease of manufacture, low material cost, variety of fiber texture, densities 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-29 US disclosed
WO-2005115618-A1 MACROPOROUS ION EXCHANGE RESINS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-08 WO disclosed
US-20050261384-A1 MACROPOROUS ION EXCHANGE RESINS 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-20050261385-A1 Macroporous ion exchange resins 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-6590094-B2 Methacrylate resin for use as tool in genetic analysis BAYER AKTIENGESELLSCHAFT (DE) 2003-07-08 US disclosed
US-20020106659-A1 Methacrylate resin for use as tool in genetic analysis BAYER AKTIENGESELLSCHAFT (DE) 2002-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059731-A1 Method for Biomaterial Purification and Kits Thereof BMP2, ADM2, PLOD3 HTT 4293/4885POLB 1027/4885SMN1; SMN2 4173/4885
US-12630582-B2 Method for biomaterial purification and kits thereof CD68, FIBP, BMP2 HTT 4325/4885POLB 574/4885SMN1; SMN2 3006/4885
US-20240010674-A1 A FILTRATION UNIT AND A METHOD FOR BIOMATERIAL PURIFICATION CD68, PLAUR, BMP2 HTT 4050/4885POLB 2997/4885SMN1; SMN2 4596/4885
US-11827864-B2 Wipe with a guanidinyl-containing polymer GNPDA1, GDA, PGLS HTT 2030/4885POLB 2522/4885SMN1; SMN2 2566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.