Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12387047 | 0.79 | KMT2A (0.64) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL904513 | 0.76 | NR1H4 (0.54) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL911203 | 0.74 | MEN1 (0.57) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL1147727 | 0.74 | MEN1 (0.57) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL1068265 | 0.74 | MEN1 (0.85) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL911202 | 0.73 | MEN1 (0.56) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL20358056 | 0.72 | KMT2A (0.66) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL438314 | 0.72 | MEN1 (0.70) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL11100803 | 0.72 | NR1H4 (0.72) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL2318131 | 0.70 | MEN1 (0.68) | MAPTKMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848945-B1 | Compositions comprising a dibenzoylmethane derivate, a 1,3,5-triazinederivative and a benzalmalonate silicone derivative and their use | OREAL (FR) | 1999-10-06 | — | — | EP | claimed |
| US-9505862-B2 | Polymers containing an acetoacetate moiety | ISP INVESTMENTS LLC (US) | 2016-11-29 | — | — | US | disclosed |
| US-9334351-B2 | 4- and 5-substituted 1,2,3-triazole, and regioisomer mixtures thereof, modified polymers | ISP INVESTMENTS INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-20150051352-A1 | MULTI-FUNCTIONAL GRAFTED POLYMERS | ISP INVESTMENTS INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150005465-A1 | POLYMERS CONTAINING AN ACETOACETATE MOIETY | AVOCA LLC | 2015-01-01 | — | — | US | disclosed |
| US-20050025736-A1 | Hair and skin altering and protecting compositions | ISP INVESTMENTS INC. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050025736-A1 | Hair and skin altering and protecting compositions | CUTA, DOT1L, PTMA | MAPT 2648/4885KMT2A 65/4885MEN1 1256/4885 |
| US-20150051352-A1 | MULTI-FUNCTIONAL GRAFTED POLYMERS | PAICS, ODC1, GANC | MAPT 4437/4885KMT2A 3266/4885MEN1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.