SCHEMBL6316507

SCHEMBL6316507

CC(C)(C)OC(=O)C=CF

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
APLNR P35414 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
XPO1 O14980 1/20 0.30
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375029 0.84 HCAR2 (0.45) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL43764 0.84 HCAR2 (0.45) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL43004 0.84 HCAR2 (0.45) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL27638180 0.81 HCAR2 (0.43) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL11283926 0.79 DGAT1 (0.37) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL391778 0.77 DGAT1 (0.36) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL391777 0.77 DGAT1 (0.36) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL19574338 0.77 DGAT1 (0.36) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL21521062 0.77 DGAT1 (0.36) DGAT1KEAP1NFE2L2HCAR2XPO1
SCHEMBL21115339 0.77 DGAT1 (0.36) DGAT1KEAP1NFE2L2HCAR2XPO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6872504-B2 High sensitivity X-ray photoresist MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-03-29 US claimed
US-20040110091-A1 High sensitivity X-ray photoresist MASS INSTITUTE OF TECHNOLOGY (MIT) 2004-06-10 US claimed
EP-4201408-B1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA VIFOR INT LTD (CH) 2025-06-25 EP disclosed
EP-4201408-A1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA Vifor (International) Ltd. (CH) 2023-06-28 EP disclosed
EP-3431094-B1 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA VIFOR INT LTD (CH) 2022-12-07 EP disclosed
US-6872504-B2 High sensitivity X-ray photoresist MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-03-29 US disclosed
US-20040110091-A1 High sensitivity X-ray photoresist MASS INSTITUTE OF TECHNOLOGY (MIT) 2004-06-10 US disclosed