Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19574338 | 1.00 | DGAT1 (0.36) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL43004 | 0.86 | HCAR2 (0.45) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL43764 | 0.86 | HCAR2 (0.45) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL375029 | 0.86 | HCAR2 (0.45) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL11283926 | 0.81 | DGAT1 (0.37) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL19008840 | 0.79 | HCAR2 (0.39) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL391778 | 0.79 | DGAT1 (0.36) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL28613967 | 0.79 | DGAT1 (0.36) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL21521062 | 0.79 | DGAT1 (0.36) | DGAT1KEAP1NFE2L2HCAR2XPO1 | |
| SCHEMBL391777 | 0.79 | DGAT1 (0.36) | DGAT1KEAP1NFE2L2HCAR2XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234238-B2 | Antimicrobial compounds and methods of making and using the same | BioVersys AG (CH) | 2025-02-25 | — | — | US | disclosed |
| US-20240239800-A1 | PYRROLO[2,3-D]PYRIMIDIN-2-ONE ANTIMICROBIAL COMPOUNDS | RIB-X PHARMACEUTICALS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20210253589-A1 | AMINOMETHYLAMIDINE AND METHYLAMIDINE ANTIMICROBIAL COMPOUNDS | BioVersys AG (CH) | 2021-08-19 | — | — | US | disclosed |
| US-10815237-B2 | Antimicrobials and methods of making and using same | BioVersys AG (CH) | 2020-10-27 | — | — | US | disclosed |
| US-20190194205-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | MELINTA THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194205-A1 | ANTIMICROBIALS AND METHODS OF MAKING AND USING SAME | LPO, OAT, MPO | DGAT1 1530/4885KEAP1 392/4885NFE2L2 688/4885 |
| US-10815237-B2 | Antimicrobials and methods of making and using same | LPO, OAT, MPO | DGAT1 1530/4885KEAP1 392/4885NFE2L2 688/4885 |
| US-12234238-B2 | Antimicrobial compounds and methods of making and using the same | LPO, MPO, OAT | DGAT1 1676/4885KEAP1 163/4885NFE2L2 284/4885 |
| US-20240239800-A1 | PYRROLO[2,3-D]PYRIMIDIN-2-ONE ANTIMICROBIAL COMPOUNDS | LPO, MAVS, FPR2 | DGAT1 2160/4885KEAP1 886/4885NFE2L2 200/4885 |
| US-20210253589-A1 | AMINOMETHYLAMIDINE AND METHYLAMIDINE ANTIMICROBIAL COMPOUNDS | MTAP, PRMT3, AMPD2 | DGAT1 2408/4885KEAP1 2169/4885NFE2L2 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.