Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250456 | 0.73 | TSHR (0.40) | — | |
| SCHEMBL631670 | 0.70 | TSHR (0.41) | LMNA | |
| SCHEMBL6534591 | 0.69 | RGS12 (0.34) | — | |
| SCHEMBL2400835 | 0.67 | CA1 (0.38) | — | |
| SCHEMBL2400089 | 0.67 | CA1 (0.38) | — | |
| SCHEMBL1332682 | 0.66 | TSHR (0.42) | LMNA | |
| SCHEMBL27869193 | 0.63 | KMT2A (0.34) | LMNA | |
| SCHEMBL19480616 | 0.63 | PAOX (0.43) | LMNA | |
| SCHEMBL9547901 | 0.62 | ALDH1A1 (0.43) | LMNA | |
| SCHEMBL9324925 | 0.62 | LMNA (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064256-B1 | BICYCLO [2.2.1] HEPTANES AND RELATED COMPOUNDS | PFIZER PROD INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1396273-A1 | Bicyclo(2.2.1.)heptanes and related compounds | Pfizer Products Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| EP-1064256-A1 | BICYCLO [2.2.1] HEPTANES AND RELATED COMPOUNDS | Pfizer Products Inc. (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6136861-A | Bicyclo[2.2.1]heptanes and related compounds | PFIZER INC (US) | 2000-10-24 | — | — | US | disclosed |
| WO-1999047490-A1 | BICYCLO[2.2.1]HEPTANES AND RELATED COMPOUNDS | PFIZER PRODUCTS INC. (US) | 1999-09-23 | — | — | WO | disclosed |