Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404786 | 0.77 | MEN1 (0.44) | MAPTALDH1A1L3MBTL1TDP1LMNA | |
| SCHEMBL8533642 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL810175 | 0.72 | HDAC4 (0.48) | MAPTALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL20686609 | 0.71 | ALDH1A1 (0.43) | MAPTALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL6942981 | 0.71 | MAPT (0.60) | MAPTALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL28178057 | 0.71 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| Benzophenone SCHEMBL27766299 | 0.70 | ALDH1A1 (0.82) | MAPTALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL2081539 | 0.70 | MT-CO2 (0.40) | MAPTALDH1A1KMT2A | |
| Benzophenone SCHEMBL30536983 | 0.67 | ALDH1A1 (1.00) | MAPTALDH1A1L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL28491203 | 0.67 | ALDH1A1 (1.00) | MAPTALDH1A1L3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969697-B2 | Substituted benzoylcyclohexenones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-29 | — | — | US | claimed |