Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 13/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 11/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 11/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309658 | 0.89 | ITGAL (0.52) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL6317720 | 0.88 | ITGAL (0.51) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL6310688 | 0.84 | ITGAL (0.48) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL6317608 | 0.84 | RAB9A (0.48) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL6318617 | 0.81 | RAB9A (0.49) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL6919943 | 0.81 | ITGAL (0.52) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL6312958 | 0.80 | ITGB2 (0.41) | ITGALITGB2ICAM1KDM4E | |
| SCHEMBL6318327 | 0.80 | SMN1; SMN2 (0.55) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL7618990 | 0.80 | ITGAL (0.60) | ITGALITGB2ICAM1RAB9ANPC1 | |
| SCHEMBL6310203 | 0.79 | ITGAL (0.49) | ITGALITGB2ICAM1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |