Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610906 | 0.83 | ESR1 (0.41) | ESR1ESR2TAAR1TRPA1ATM | |
| SCHEMBL811980 | 0.82 | TAAR1 (0.52) | TAAR1TSHRSMN1; SMN2MAPTGAA | |
| SCHEMBL17077902 | 0.80 | TDP2 (0.32) | — | |
| SCHEMBL16958334 | 0.79 | ALDH1A1 (0.42) | TAAR1GABRA1GABRB2SMN1; SMN2MAPT | |
| SCHEMBL16952334 | 0.79 | GABRA1 (0.38) | TAAR1GABRA1GABRB2P2RX7ALDH1A1 | |
| SCHEMBL3792645 | 0.78 | ESR1 (0.41) | ESR1ESR2TAAR1TRPA1ATM | |
| SCHEMBL8010290 | 0.77 | GABRA1 (0.44) | ESR1ESR2TRPA1ATMGABRA1 | |
| SCHEMBL29420847 | 0.77 | GABRA1 (0.50) | ESR1ESR2TAAR1TRPA1ATM | |
| SCHEMBL140570 | 0.77 | GABRA1 (0.50) | ESR1ESR2TAAR1TRPA1ATM | |
| SCHEMBL4094425 | 0.76 | SCN8A (0.37) | TAAR1TSHRSMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | claimed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | claimed |
| EP-0469887-A1 | Acetamide derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| US-20050158264-A1 | Sympathetic nerve-stimulating fragrant compositions | SHISEIDO COMPANY, LTD. | 2005-07-21 | — | — | US | disclosed |
| US-20050003976-A1 | Sympathetic nerve-stimulating fragrant compositions | SHISEIDO COMPANY, LTD. | 2005-01-06 | — | — | US | disclosed |
| EP-1346726-A1 | SYMPATHETIC-ACTIVATING PERFUME COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| EP-0469887-B1 | Acetamide derivatives | ZENECA LTD (GB) | 1994-12-14 | — | — | EP | disclosed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| EP-0469887-A1 | Acetamide derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-3933806-A | Cephalosporin michael adducts | ELI LILLY AND COMPANY (US) | 1976-01-20 | — | — | US | disclosed |