Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381491 | 0.88 | CCR4 (0.53) | CCR4ITGB1ITGA5FKBP1AALDH1A1 | |
| SCHEMBL630983 | 0.88 | CCR4 (0.53) | CCR4ITGB1ITGA5FKBP1AALDH1A1 | |
| SCHEMBL8268314 | 0.87 | ITGB1 (0.51) | CCR4ITGB1ITGA5FKBP1AALDH1A1 | |
| SCHEMBL8268337 | 0.87 | ITGB1 (0.51) | CCR4ITGB1ITGA5FKBP1AALDH1A1 | |
| SCHEMBL630070 | 0.79 | FKBP1A (0.56) | CCR4ITGB1ITGA5FKBP1AALDH1A1 | |
| SCHEMBL1384306 | 0.79 | FKBP1A (0.56) | CCR4ITGB1ITGA5FKBP1AALDH1A1 | |
| SCHEMBL1383786 | 0.76 | FKBP1A (0.53) | ITGB1ITGA5FKBP1AALDH1A1MAPK1 | |
| SCHEMBL630215 | 0.76 | FKBP1A (0.53) | ITGB1ITGA5FKBP1AALDH1A1MAPK1 | |
| SCHEMBL629939 | 0.75 | CCR4 (0.43) | CCR4ITGB1ITGA5FKBP1AALDH1A1 | |
| SCHEMBL1381571 | 0.75 | FKBP1A (0.52) | ITGB1ITGA5FKBP1AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |