SCHEMBL6664519

SCHEMBL6664519

CC(N)NCc1ccc(Cl)nc1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
GAA P10253 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPT P10636 1/20 0.51
ALDH1A1 P00352 3/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 1/20 0.43
KDM1A O60341 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
OXTR P30559 1/20 0.41
AVPR1A P37288 1/20 0.41
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30493956 0.86 KDM4E (0.54) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL7660114 0.86 KDM4E (0.54) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL10440420 0.85 CHRNB2 (0.41) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL28781673 0.83 KDM4E (0.51) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL6317403 0.80 KDM4E (0.49) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL5049626 0.78 ALDH1A1 (0.48) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL3824431 0.77 SLC6A2 (0.57)
SCHEMBL27977498 0.76 KDM4E (0.51) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL18884421 0.76 GAA (0.59) KDM4EGAAL3MBTL1MAPTALDH1A1
SCHEMBL29609117 0.76 KDM4E (0.59) KDM4EGAAL3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7242633-A None JP disclosed
EP-0970052-B1 METHOD FOR PRODUCING 5-AMINOMETHYL-2-CHLOROPYRIDINES BAYER CROPSCIENCE AG (DE) 2004-08-11 EP disclosed
US-6150528-A Method for producing 5-aminomethyl-2-chloropyridines BAYER AKTIENGESELLSCHAFT (DE) 2000-11-21 US disclosed
EP-0970052-A1 METHOD FOR PRODUCING 5-AMINOMETHYL-2-CHLOROPYRIDINES BAYER AG (DE) 2000-01-12 EP disclosed
WO-1998041504-A1 METHOD FOR PRODUCING 5-AMINOMETHYL-2-CHLOROPYRIDINES BAYER AKTIENGESELLSCHAFT (DE) 1998-09-24 WO disclosed
JP-H07242633-A PRODUCTION OF 5-AMINOETHYLAMINOMETHYL-2-CHLOROPYRIDINE ISHIHARA SANGYO KAISHA LTD 1995-09-19 JP disclosed