SCHEMBL6317684

SCHEMBL6317684

CC1(c2ccccc2)CCCC(C)(c2ccccc2)N1[O]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HSD11B1 P28845 2/20 0.40
BACE1 P56817 1/20 0.40
AKR1C1 Q04828 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRK1 P41145 1/20 0.39
OPRL1 P41146 1/20 0.39
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
CYP2B6 P20813 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
PRCP P42785 1/20 0.37
SLC6A3 Q01959 1/20 0.37
GRIN1 Q05586 1/20 0.37
KCNH2 Q12809 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3389799 0.91 ALDH1A1 (0.43) ALDH1A1HSD11B1BACE1AKR1C1OPRM1
SCHEMBL444597 0.90 ALDH1A1 (0.38) ALDH1A1HSD11B1BACE1AKR1C1OPRM1
SCHEMBL440388 0.82 ALDH1A1 (0.40) ALDH1A1HSD11B1BACE1OPRM1OPRK1
SCHEMBL5466007 0.79 ALDH1A1 (0.41) ALDH1A1HSD11B1AKR1C1OPRM1OPRK1
SCHEMBL18812549 0.75 OPRM1 (0.46) OPRM1OPRK1OPRL1GRIN2DGRIN3B
SCHEMBL5343015 0.75 ALDH1A1 (0.39) ALDH1A1BACE1KCNH2
SCHEMBL444598 0.75 ALDH1A1 (0.38) ALDH1A1HSD11B1AKR1C1OPRM1OPRK1
SCHEMBL4296257 0.73 OPRM1 (0.44) ALDH1A1OPRM1GRIN2DGRIN3BCYP2B6
SCHEMBL8552014 0.73 GRIN2D (0.48) HSD11B1OPRM1GRIN2DGRIN3BCYP2B6
SCHEMBL29082026 0.72 GRIN1 (0.47) ALDH1A1HSD11B1OPRM1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6239226-B1 Block copolymers BASF AKTIENGESELLSHCAFT (DE) 2001-05-29 US claimed
US-6916893-B2 Polymerization-active transition metal complexes having bulky ligand systems SER. V. GMBH (DE) 2005-07-12 US disclosed
US-20040171774-A1 Polymerization-active transition metal complexes having bulky ligand systems RIEGER BERNHARD (DE) 2004-09-02 US disclosed
EP-1398330-A2 Transition metal complexes having a bulky ligand system used in polymerisation Ser.V. GmbH (DE) 2004-03-17 EP disclosed
EP-1054913-B1 METHOD FOR THE PRODUCTION OF POLYMERS FROM N-VINYL COMPOUNDS BASF AG (DE) 2003-04-23 EP disclosed
EP-0876404-B1 PROCESS FOR PREPARING AN AQUEOUS POLYMER DISPERSION BY THE METHOD OF RADICAL AQUEOUS EMULSION POLYMERIZATION BASF AG (DE) 2003-04-09 EP disclosed
EP-1192197-B1 METHOD FOR PRODUCING GRAFT COPOLYMERS, CONTAINING AN ELASTIC GRAFT COPOLYMER BACKBONE BASF AG (DE) 2002-12-04 EP disclosed
US-6380315-B1 FREE RADICAL POLYMERIZATION BASF AKTIENGESELLSCHAFT (DE) 2002-04-30 US disclosed
US-6369165-B1 ADDITION POLYMERIZATION IN PRESENCE OF 1,2,4-TRIAZOLE, THIATRIAZOLE, 1,2,4-THIADIAZOLE, AND/OR DITHIADIAZOLE FREE RADICAL DERIVATIVES BASF AKIENGESELLSCHAFT & MAX-PLANCK-GESELLSCHAFT (DE) 2002-04-09 US disclosed
US-20010034415-A1 Impact-modified thermoplastic polymer mixtures based on SO2 copolymers having an aliphatic main chain BASF AKTIENGESELLSCHAFT (DE) 2001-10-25 US disclosed
US-6008303-A Polymers suitable as dispersing resins BASF AKTIENGESELLSCHAFT (DE) 1999-12-28 US disclosed
WO-1999047569-A1 METHOD FOR PRODUCING COPOLYMERS FROM FUNCTIONALISED OLEFINICALLY UNSATURATED MONOMERS AND NON-POLAR OLEFINICALLY UNSATURATED COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1999-09-23 WO disclosed
EP-0876414-B1 BLOCK COPOLYMERS BASF AG (DE) 1999-08-25 EP disclosed
EP-0876414-A1 BLOCK COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 1998-11-11 EP disclosed
EP-0876413-A1 POLYMERS SUITABLE AS DISPERSING RESINS BASF AKTIENGESELLSCHAFT (DE) 1998-11-11 EP disclosed
EP-0876404-A1 PROCESS FOR PREPARING AN AQUEOUS POLYMER DISPERSION BY THE METHOD OF RADICAL AQUEOUS EMULSION POLYMERIZATION BASF AKTIENGESELLSCHAFT (DE) 1998-11-11 EP disclosed
WO-1997027232-A1 POLYMERS SUITABLE AS DISPERSING RESINS BASF AKTIENGESELLSCHAFT (DE) 1997-07-31 WO disclosed
WO-1997027222-A1 PROCESS FOR PREPARING AN AQUEOUS POLYMER DISPERSION BY THE METHOD OF RADICAL AQUEOUS EMULSION POLYMERIZATION BASF AKTIENGESELLSCHAFT (DE) 1997-07-31 WO disclosed
WO-1997027233-A1 BLOCK COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 1997-07-31 WO disclosed
WO-1997027582-A1 MAGNETIC RECORDING MEDIUM EMTEC MAGNETICS GMBH (DE) 1997-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171774-A1 Polymerization-active transition metal complexes having bulky ligand systems AP1M1, CCNC, CLTB ALDH1A1 2788/4885HSD11B1 4246/4885BACE1 3662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.