Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768289 | 0.93 | TSHR (0.54) | TSHRMAPK1CES2MGLLHTR3E | |
| SCHEMBL62723 | 0.87 | TSHR (0.67) | TSHRMAPK1CES2MGLLHTR3E | |
| SCHEMBL25489557 | 0.85 | TSHR (0.54) | TSHRMAPK1CES2MGLLHTR3E | |
| SCHEMBL22932515 | 0.85 | TSHR (0.54) | TSHRMAPK1CES2MGLLHTR3E | |
| Methyl Alcohol SCHEMBL9419583 | 0.84 | TSHR (0.58) | TSHRMAPK1CES2MGLLHTR3E | |
| SCHEMBL30553105 | 0.84 | TSHR (0.64) | TSHRMAPK1CES2MGLLHTR3E | |
| Fluoride SCHEMBL30661872 | 0.84 | TSHR (0.64) | TSHRMAPK1CES2MGLLHTR3E | |
| SCHEMBL28126330 | 0.84 | TSHR (0.64) | TSHRMAPK1CES2MGLLHTR3E | |
| Benzene SCHEMBL8568955 | 0.84 | TSHR (0.67) | TSHRMAPK1CES2MGLLHTR3E | |
| SCHEMBL30252943 | 0.84 | TSHR (0.64) | TSHRMAPK1CES2MGLLHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282982-A1 | Amido complexes of vanadium for olefin polymerization | LANXESS DEUTSCHLAND GMBH (DE) | 2005-12-22 | — | — | US | disclosed |
| EP-0800116-B1 | Photoresist composition | MITSUBISHI CHEM CORP (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0895127-A2 | Photoresist composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-02-03 | — | — | EP | disclosed |
| US-5759736-A | Photoresist composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0800116-A1 | Photoresist composition | Mitsubishi Chemical Corporation (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-4792635-A | Symmetric benzophenones substituted by groups containing fluorine | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| EP-0156278-B1 | PROCESS FOR THE PREPARATION OF SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS, THEIR USE AND SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0156278-A2 | Process for the preparation of symmetrical benzophenones substituted by fluor-containing groups, their use and symmetrical benzophenones substituted by fluor-containing groups | BAYER AG (DE) | 1985-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282982-A1 | Amido complexes of vanadium for olefin polymerization | NOX4, NOXO1, COG4 | TSHR 4760/4885MAPK1 3477/4885CES2 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.